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Low testosterone can lead to higher diabetes risk

Most people think of type 2 diabetes as a diet and lifestyle issue but in men, low testosterone plays a major role. Men with the lowest free testosterone are 3-4x more likely to have diabetes.

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Haider KS, Haider A, Saad F, et al. Remission of type 2 diabetes following long-term treatment with injectable testosterone undecanoate in patients with hypogonadism and type 2 diabetes: 11-year data from a real-world registry study. Diabetes Obes Metab. 2020; 22:2055–2068. https://doi.org/10.1111/dom.14122

Testosterone therapy helps prevent type 2 diabetes

Prevalence

Men with low testosterone have 4x greater risk of type 2 diabetes

DIAGNOSIS

TRT reduces the risk of developing type 2 diabetes by 41% percent

By restoring healthy testosterone levels, TRT:

Reduces visceral fat
Enhances energy and motivation
Improves insulin sensitivity
Weight gain
Increases muscle mass
Lowers inflammation
Supports better blood sugar control
Help improve fatigue

Citations

¹ Wittert G, Bracken K, Robledo KP, et al. Testosterone treatment to prevent or revert type 2 diabetes in men enrolled in a lifestyle programme (T4DM): a randomised, double-blind, placebo-controlled, 2-year, phase 3b trial. Lancet Diabetes Endocrinol. 2021;9(1):32-45.
² Selvin E, et al. Androgens and diabetes in men: results from the Third National Health and Nutrition Examination Survey (NHANES III). Diabetes Care. 2007;30(2):234-238.
³ Based on data on MANUAL clinical care data of over 2000 patients over the last 18 months

See if TRT can help you

Protect your metabolic health for the future

Low testosterone contributes to the conditions that cause diabetes to develop — fat gain, inflammation, poor glucose control — but TRT helps reverse these risk factors early, before they become irreversible.

Lowering fasting glucose

Lower waist circumference, BMI

Lower blood pressure

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TRT may also help reverse type 2 diabetes in some men

While the focus of TRT is prevention, it’s worth noting that testosterone therapy has also shown significant benefits in men already living with diabetes.

Diabetes remission

Healthy testosterone levels support blood flow and erectile function, reducing the frequency of ED.

Lower HbA1c levels

Men with poorly controlled diabetes experienced an average drop of 4 mmol/L in HbA1c within 6 months of starting TRT.

Reduced medication

Many men were able to stop using diabetes medications entirely after consistent testosterone treatment.

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